Senior Principal Scientist, Oncology Translational Research, Cell Therapy

Job Description

Job Ttitle: Senior Principal Scientist, Oncology Translational Research, Cell Therapy

Company: Johnson & Johnson


Description: Johnson & Johnson Innovative Medicine is recruiting for Principal/Sr. Principal Scientist, located in Spring House, PA or San Diego, CA, or Raritan, NJ.At Johnson & Johnson Innovative Medicine, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.At Johnson & Johnson Innovative Medicine discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases.We are At Johnson & Johnson. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.The Cell Therapy Translational Research Group, which is a part of Oncology Translational Research is seeking an experienced translational research scientist to develop and execute translational and biomarker plans to support the clinical development of novel chimeric antigen receptor (CAR)- T cell therapies across multiple disease indications.The incumbent will provide scientific leadership in preclinical and clinical translational research programs with a focus on CAR-T cell therapy. To this end the incumbent will be expected to develop strong collaborations and influence across the Oncology Therapeutic Area, leveraging expertise in the Discovery and Clinical organizations as needed. Additionally, the incumbent will be expected to develop scientific collaborations external to the organization in support of reverse translation efforts that will enable the interrogation of clinical samples to provide novel insights into disease biology and mechanisms of efficacy and safety. Details of the role include but are not limited to:

• Develop and implement the translational strategy for the CAR-T cell therapy compound, participate in the compound development team and/or relevant working groups, independently or working with senior translational research leads
• Guide working groups to implement cell therapy translational strategy and manage ongoing programs and projects
• Develop, implement, and deliver on translational research collaborations and projects, including initial proposal development, planning timelines and resources, monitoring milestones and final deliverables
• Work closely across groups and functions to explore novel indications and new drug combinations for compounds in clinical development
• Communicate project deliverables to the leaders across the Oncology therapeutic area (TA), and other senior governance groups when necessary
• Interact and liaison with internal experts, external experts, academic groups, and CROs to establish collaborations and projects
• Fulfill regulatory responsibilities including preparing, updating, and finalizing clinical/preclinical sections for clinical protocols and other regulatory documents

Qualifications

• Ph.D. with experience in CAR-T cell therapy and/or immune oncology is required.
• At least five years of applicable translational, biomarker or clinical trial and research experience is required, preferably in an industrial setting.
• Strong publication record in cell therapy and/or immune oncology is highly preferred
• Experience guiding cross functional groups in a matrix environment is required
• Experience working closely with groups involved in biomarker operations, assay development/validation and external CROs is required
• Familiarity with the techniques common to translational research including, but not limited to, flow cytometry, genomics, proteomics and importantly, data analysis and specifically correlative analysis are required
• Relevant experience in clinical trials, drug development, drug discovery or biomarkers is required
• Experience in managing multi-faceted projects and programs is preferred
• Strong communication skills are required

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.The anticipated base pay range for this position is $137,000 to $235,750.The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis.

• Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
• Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
• This position is eligible to participate in the Company’s long-term incentive program.
• Employees are eligible for the following time off benefits:
• Vacation – up to 120 hours per calendar year
• Sick time – up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year
• Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time – up to 40 hours per calendar year
• Additional information can be found through the link below.

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market

Salary:

Location: San Diego, CA

Date: Thu, 05 Dec 2024 08:56:59 GMT


Read More…